Natalie Talmadge was the middle daughter of the original "stage mother", Margaret Talmadge (Peg). Her two sisters, Constance Talmadge (the comedienne) and Norma Talmadge (the tragedian) were also in the movies, and had their own production companies, bankrolled by Norma's husband in the 1920s, Joseph M. Schenck . Natalie married Buster Keaton in 1921. She only played one further role, "Virginia Canfield" in Keaton's Our Hospitality (1923). She had worked for Comique as a script girl/secretary for Roscoe 'Fatty' Arbuckle in 1917, and traveled west with the troupe when Schenck found new premises for "Roscoe" in California. She spent a lot of time signing autographs on behalf of her popular sister, Contance. Anita Loos , author of "Gentlemen Prefer Blondes", wrote a book called "The Talmadge Girls", which is mainly about Constance and Norma; Loos based the philosophy of "Lorelei Lee" on the philosophy of Peg Talmadge ("Get the money, and then get comfortable"). Natalie ended her days after her divorce from Keaton in a house in Santa Monica, a confirmed alcoholic. Apart from "Our Hospitality", she appeared in supporting roles in several of her sister Norma's films (now believed to be lost).

Daughter of Margaret TalmadgeMiddle sister of Norma Talmadge and Constance Talmadge .Entire west wing of Italian Villa was hers; dressingrooms packed with clothes she never even wore.In 1927, the Talmadge sisters opened the Talmadge Park real estate development in San Diego, California, USA. Now known as the Talmadge district, the development contains streets named for each of the sisters. The district is located about one mile southwest of the San Diego State University campus.Three months pregnant with her second son, Bob Talmadge (Robert), when principle photography for Our Hospitality (1923) began.On her wedding day to Buster Keaton , her sisters gave her a modified 1920 Mercer Series 5 Raceabout. (typical of high end cars of the era, it received a customized body. Murphy Coachworks of Pasadena extended the cowl, installed a taller windshield and added a door on the right side). Buster drove the car in Three Ages (1923). A color photo of the car, which still exists, was printed in the February 1993 issue of Road & Track (USA).Like her sisters, her grave marker gives a false date of birth (1900).Embittered after her divorce from Buster Keaton , she had her son's name legally changed from Robert Keaton to Robert Talmadge. She never remarried.Mother, with Buster Keaton , of sons Bob Talmadge and Buster Keaton Jr. .